By using physics to influence biology, Novocure discovered another way to treat cancer. Tumor Treating Fields utilizes the natural electrical properties of dividing cancer cells.
what is tumor treating fields?
Tumor Treating Fields is a cancer therapy that uses electric fields tuned to specific frequencies to disrupt cell division, inhibiting tumor growth and causing affected cancer cells to die.
what is an electric field?
An electric field is a field of force. Electric fields surround all charged objects. An electric field exerts forces on other charged objects within it.
Tumor Treating Fields describes electric fields that alternate 100,000 to 300,000 times per second to target cancer cells
treating cancer with electric fields
Tumor Treating Fields uses alternating electric fields specifically tuned to target cancer cells. Once the electric fields enter the cancer cell, they attract and repel charged proteins during cancer cell division.
I find it fascinating that a fundamental physical entity, such as an electric field, can have such profound effect on cancerous cells.
Director of Science
tumor treating fields utilizes the natural electrical properties of dividing cancer cells
Cellular proteins such as tubulin and septin are strongly affected by Tumor Treating Fields because they are highly polar, containing both positive and negative charges. During cell division, tubulin and septin must position themselves in a particular way in order for the cell to divide. Tumor Treating Fields exerts forces on tubulin and septin, preventing them from moving to their correct locations and disrupting cancer cell division.
tumor treating fields causes minimal damage to healthy cells
Tumor Treating Fields does not stimulate or heat tissue and targets dividing cancer cells of a specific size. Tumor Treating Fields causes minimal damage to healthy cells. Mild to moderate skin irritation is the most common side effect reported.
tumor treating fields shows promise across a variety of solid tumor cancers
Tumor Treating Fields is approved for the treatment of adults with glioblastoma, the most common primary brain cancer in adults and one of the most difficult cancer types to treat. The therapy shows promise in multiple solid tumor types—including some of the most aggressive forms of cancer.
clinical trialsOur mechanism of action is broadly applicable across a variety of solid tumors.
novocuretrial.comThe science of Tumor Treating Fields extends beyond glioblastoma. We are conducting clinical trials in brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer and mesothelioma.